DMtools A data mining toolbox with caching of database queries and parallelism within a collection of independent queries. [Open Source, GPL] http://datamining.anu.edu.au/software/dmtools/
MetaKit for Python A Python interface to MetaKit. MetaKit is an embeddable database which runs on Unix, Windows, Macintosh, and other platforms. [Open-Source, MIT] http://www.equi4.com/metakit/python.html
Metakit for Python (Mk4py) A lower-level API for the Metakit C++ core extension, and uses SCXX by Gordon McMillan as C++ glue interface. [X/MIT-style and commercial licenses] http://www.equi4.com/metakit/
mxBeeBase On-disk B+Tree Based Database Kit. [Open Source] http://www.egenix.com/products/python/mxBase/mxBeeBase/
PDO Python Database Objects provides a convenient Object Oriented API for database access in Python. PDO supports multiple RDBMS with the same API, and provides features not found in the DB-API spec, such as column access by name. [OPen source, BSD style license] http://pdo.neurokode.com/
pSQL A wrapper above MySQLdb which renders MySQL databases as very comfortable pythonic objects. http://software.fionet.com/pSQL/
pyBSDdb Python bindings for BerkeleyDB 3.x embeddable database. [Open Source, BSD-like] http://pybsddb.sourceforge.net/
PyDO2 An ORM (Object-Relational Mapper) database access library for Python. [Open Source, GPL] http://skunkweb.sourceforge.net/pydo2.html
Python Database Row Module This Python 2.2 module defines light-weight objects which allow very flexible access to a fixed number of positional and named attributes via several interfaces. [Open Source, BSD-like] http://opensource.theopalgroup.com/
Python SQL Database Access System A simple and consistent programming interface to SQL databases, in Python. [Open source, Python Software Foundation License] http://sourceforge.net/projects/pysqldb/
SnakeDb An easy database API that is a wrapper around other Python database modules (like Gadfly and MySQLdb). [Open source, GPL] http://sourceforge.net/projects/snakedb/
SQLAlchemy SQL toolkit and Object Relational Mapper that gives application developers the full power and flexibility of SQL. [Open Source, MIT license] http://www.sqlalchemy.org/
SQLObject An Object Relational Manager for providing an object interface to your database, with tables as classes, rows as instances, and columns as attributes. [Open Source, LGPL] http://www.sqlobject.org/
ZODB The Z Object Database, or the ZODB for short, is a powerful and easy-to-use object persistence system for Python. [Open Source, ZPL] http://wiki.zope.org/ZODB/FrontPage
ZODB-Tutorial.py A number of hands-on code example how to use the ZODB. http://www.h7.dion.ne.jp/~harm/ZODB-Tutorial.py